Thank you very much for your interest in our group.

We form a small laboratory at Charité – University Medicine Berlin and focus on the following central questions:

  • How does the human brain respond to focal stimuli applied by invasive and noninvasive neuromodulation methods
    • Specifically, we study the effects of deep brain stimulation on small brain nuclei
  • How do distributed brain networks respond to such stimuli
    • We use noninvasive techniques like resting-state fMRI and diffusion-weighted MRI to address this question
  • How does DBS electrode placement affect
    • Clinical
    • Neural
    • or behavioral response

In second line, we’re highly interested in structural and functional connectomics as well as detailed anatomical definitions of the human brain.

Some of our lab members take part in developing the open-source toolbox Lead-DBS – which has become a multi-institutional endeavor.

Andreas Horn

Andreas is interested in connectivity and causality in the brain, the human connectome and its structure-function relationship. As a clinical case of connectomics, he studies effects of deep brain stimulation on aberrant circuitries that lead to movement disorders. Both interests are often realized by furthering development of the Lead-DBS toolbox.

Ningfei Li

Ningfei is a core developer of Lead-DBS with a computer science background. He focuses on connectomic deep brain stimulation analyses in the fields of Parkinson’s Disease, Dystonia and Obsessive Compulsive Disorders.

Simón Oxenford

Simón joined us to do his PhD and has a computer science background. He is part of the core development team of Lead-DBS. In his PhD, he is exploring methods to refine registration tools and to use these methods to build more predictive models for DBS.

Barbara Hollunder

Barbara is pursuing her PhD in the Einstein Center for Neurosciences PhD-program and is currently working on network effects of subthalamic stimulation with a focus of non-motor symptoms.

Qiang Wang

Qiang Wang is working on his PhD under Andrea Kühn and Andreas Horn.

Leon Sobesky

Leon is a medical student working for his dissertation at the lab.

Ana Sofía Ríos Infante

Ana is carrying out her Master’s thesis in the lab and is enrolled with the Medical Neuroscience program of Charité. She is investigating deep brain stimulation for treatment of Alzheimer’s disease.

Bassam Al-Fatly

Bassam, an MD/PhD student in the laboratory of Andrea Kühn is also affiliated with the netstim lab via multiple projects. Bassam is interested in the utility of connectomics to predict deep brain stimulation outcome in movement disorders. By those means, he focuses on optimizing deep brain stimulation therapy.

Jan Roediger

Jan is a physician interested in the translational principles of Deep Brain Stimulation. His research is focussing on the local and network effects of DBS in patients with Parkinsons Disease and aims at moving Neuroimaging from bench to bedside to optimize therapeutic strategies in the field. He is enrolled in the MD/PhD program of the Einstein Center for Neurosciences and affiliated with the Lab of Andrea Kühn.